Nonword Repetition as a Behavioural Marker for Inherited Language Impairment: Evidence From a Twin Study
Corresponding Author
D. V. M. Bishop
MRC Applied Psychology Unit. Cambridge. U.K.
Requests for reprints to: Dr Dorothy Bishop. MRC Applied Psychology Unit. 15 Chaucer Road, Cambridge, CB2 2EF, U.K.Search for more papers by this authorC. Donlan
National Hospitals College of Speech Sciences, London, U.K.
Search for more papers by this authorCorresponding Author
D. V. M. Bishop
MRC Applied Psychology Unit. Cambridge. U.K.
Requests for reprints to: Dr Dorothy Bishop. MRC Applied Psychology Unit. 15 Chaucer Road, Cambridge, CB2 2EF, U.K.Search for more papers by this authorC. Donlan
National Hospitals College of Speech Sciences, London, U.K.
Search for more papers by this authorAbstract
The Children's Nonword Repetition Test (CNRep) was given to 39 children with persistent language impairment (LI), 13 with a history of having received speech-language therapy (resolved LI), and 79 controls, all aged from 7 to 9 years. The children with LI were twins who had participated in a previous genetic study. Children with resolved LI, as well as those with persistent LI. were significantly impaired on the CNRep. Comparisons of MZ and DZ twins indicated significant heritability of a CNRep deficit. It is concluded that CNRep provides a marker of the phenotype of heritable forms of developmental language impairment.
References
-
Adams, A.-M. &
Gathercole, S. E. (1995). Phonological working memory and speech production in preschool children.
Journal of Speech and Heating Research, 38, 403–414.
-
American Psychiatric Associationz (1987), Diagnostic and statistical manual-3rd edition, revised (DSM-III-R).
Washington
,
DC
: APA.
-
Anthony, A.,
Bogle, D.,
Ingram, T. T. S, &
Mclsaac, M. W. (1971). The Edinburgh Articulation Test.
Edinburgh
: Churchill Livingstone.
-
Baddeley, A. D. (1993). Short-term phonological memory and long-term learning: a single case study.
European Journal of Cognitive Psychology. 5, 129–148.
-
Bishop, D. V. M. (1983). The Test for Reception of Grammar. Published by the author and available from Age and Cognitive Performance Research Centre. University of Manchester, MI3 9PL.
-
Bishop, D. V. M. (1992). The underlying nature of specific language impairment.
Journal of Child Psychology and Psychiatry, 33, 1–64.
-
Bishop, D. V. M. (1994). Is specific language impairment a valid diagnostic category? Genetic and psycho)inguistic evidence.
Philosophical transactions of the Royal Society, series B. 346, 105–111.
-
Bishop, D. V. M. &
Adams. C. (1990). A prospective study of the relationship between specific language impairment, phonological disorders and reading retardation.
Journal of Child Psychology and Psychiatry, 31, 1027–050.
-
Bishop, D. V M.,
North, T. &
Donlan, C. (1995). Genetic basis of specific language impairment: evidence from a twin study.
Developmental Medicine and Child Neurology, 37, 56–71.
-
Crago, M. B. &
Gopnik, M. (1994). From families to phenotypes: theoretical and clinical implications of research into the genetic basis of specific language impairment. In
R. Watkins &
M. Rice, (Eds)
Specific language impairments in children (pp.
35–51).
Baltimore
: Paul H. Brookes.
-
DeFries, J. C. &
Fulker, D. W. (1988). Multiple regression analysis of twin data: aetiology of deviant scores versus individual differences.
Acta Geneticac et Medicae Gemellologiae. 37, 205–216.
-
DeFries, J. C.,
Olson, K.,
Pennington, B. F. &
Smith, S. D. (1991). Colorado Reading Project: an update. In
D. D. Duane &
D, B.
Gray (Eds).
The reading brain: the biological basis of dyslexia (pp.
53–87).
Parkton
: York Press.
-
Felton, R. H.,
Naytor, C. E. &
Wood, F. B. (1990). Neuropsychological profile of adult dyslexics.
Brain and Language, 30, 485–497.
-
Gathercole, S. E. (1995). Is nonword repetition a test of phonological working memory or long-term knowledge? It all depends on the nonwords.
Memory and Cognition. 23, 83–94.
-
Gathercole, S. E. &
Adams, A. (1993). Phonological working memory in very young children.
Developmental Psychology, 29, 770–778.
-
Gathercole, S. E. &
Baddeley, A. D. (1989). Evaluation of the role of phonological STM in the development of vocabulary in children: a longitudinal study.
Journal of Memory and Language, 28, 200–213.
-
Gathercole, S. E. &
Baddeley, A. D. (1990). Phonological memory deficits in language-disordered children: is there a causal connection
Journal of Memory and Language, 29, 336–360.
-
Gathercole, S. E.,
Willis, C.,
Emslie, H. &
Baddeley, A. D. (1991). The influences of syllables and wordlikeness on children's repetition of nonwords.
Applied Psycholinguistics, 12, 349–367.
-
Gathercote, S. E.,
Willis, C.,
Emslie, H. &
Baddeley, A. D. (1992). Phonological memory and vocabulary development during the early school years: a longitudinal study.
Developmental Psychology, 28, 887–898.
-
Gathercole, S. E.
Willis, C.
Baddeley, A. D. &
Emslie, H. (1994). The children's test of nonword repetition: a test of phonological working memory.
Memory, 2, 103–127.
-
Gershon, E. S. &
Goldin, L. R. (1986). Clinical methods in psychiatric genetics: 1. Robustness of genetic marker investigative strategies.
Acta Psychiatrica Scandinavica, 74, 113–118.
-
Gross-Glenn, K.
Jallad, B.
Novoa, L.,
Helgren-Lempesis, V. &
Lubs, H. A. (1990). Nonsense passage reading as a diagnostic aid in the study of adult familial dyslexia.
Reading and Writing. 2, 161–173.
-
Guilford, J P. &
Fruchter, B. (1973). Fundamental statistics in psychology and education ( 5th Ed.).
New York
: McGraw-Hill.
-
Hay, D. A. (1985). Essentials of behaviour genetics.
Melbourne
: Blackwell Scientific.
-
Hurst, J. A.,
Barailser, M.,
Auger, E.,
Graham, F. &
Norell, S. (1990). An extended family with a dominantly inherited speech disorder.
Developmental Medicine and Child Neurology, 32, 352–355.
-
Jeffreys, A. J.,
Wilson, V.,
Them, S. L.
Weatherall, D. J. &
Ponder, B. A. (1986). DNA “fingerprints”' and segregation analysis of multiple markers in human pedigrees.
American Journal of Human Genetics, 39, 11–24.
-
Johnston, J. (1994). Cognitive abilities of children with language impairment. In
R. Watkins &
M. Rice, (Eds)
Specific language impairments in children (pp.
107–121).
Baltimore
: Paul H. Brookes.
-
Kamhi, A. G. &
Catts, H. W. (1986). Toward an understanding of developmental language and reading disorders.
Journal of Speech and Hearing Research. 57, 337–347.
-
Kamhi, A. G.,
Lee, R. &
Nelson, L. (1985). Word, syllable, and sound awareness in language-disordered children.
Journal of Speech and Hearing Disorders, 49, 169–177.
-
Lewis, B. &
Freebairn, L. (1992). Residual effects of preschool phonology disorders in grade school, adolescence, and adulthood.
Journal of Speech and Hearing Research, 35, 819–831.
-
Lewis, B. A. &
Thompson, L. A. (1992). A study of developmental speech and language disorders in twins.
Journal of Speech and Hearing Research. 35., 1086–1094.
-
Lykken, D. T.,
McGue, M. &
Tellegen, A. (1987). Recruitment bias in twin research: the rule of two-thirds reconsidered.
Behavior Genetics, 17, 343–362.
-
McKenna, P. &
Warrington, E. K. (1983). Graded Naming Test (GNT).
Windsor
: NFER-Nelson.
-
Nichols, R. C. &
Bilbro, W. C. (1966). The diagnosis of twin zygosity.
Acta deneticae Mediate et Gemellologiae, 16, 265–275.
-
Plomin, R. (1991). Genetic risk and psychosocial disorders: links between the normal and abnormal. In
M. Rutter &
P. Casaer, (Eds)
Biological risk factors for psychosocial disorders (pp.
101–138).
Cambridge
: Cambridge University Press.
-
Raven, J. C.,
Court, J. H. &
Raven, J. (1986). Raven's progressive matrices and Raven's coloured matrices.
London
: H. K. Lewis.
-
Renfrew, C. (1980). Word-finding vocabulary scale.
Oxford
: C. E. Renfrew.
-
Rice, M. (1994). Grammatical categories of children with specific language impairments. In
R. Watkins &
M. Rice, (Eds)
Specific language impairments in children (pp.
69–89).
Baltimore
: Paul H. Brookes.
-
Semel, E. M.,
Wiig, E. H. &
Secord, W. (1980). Clinical evaluation of language fundamentals-revised.
San Antonio
,
TX
: Psychological Corporation.
-
Snedecor, G. W. &
Cochran, W. G. (1989). Statistical methods ( 8th Ed.).
Iowa
: Iowa State University Press.
-
Snowling, M. (1981). Phonemic deficits in developmental dyslexia, Psychological Research, 43, 219–234.
-
Snowling, M.,
Chiat, S. &
Hulme, C. (1991). Words. nonwords, and phonological processes: some comments on Gathercole, Willis, Emslie, and Baddeley.
Applied Psycholinguistics, 12, 369–373.
-
Tallal, P.,
Stark, R. E. &
Mellits, E. D. (1985). Identification of language-impaired children on the basis of rapid perception and production skills.
Brain and Language, 25, 314–322.
-
Thapar, A.,
Petrill, S. A. &
Thompson, L. A. (1994). The heritability of memory in the Western Reserve Twin Project.
Behavior Genetics, 24, 155–160.
-
Tomblin, J. B. &
Buckwalter, P. R. (1994). Studies of genetics of specific language impairment. In
R. Waikins &
M. Rice, (Eds)
Specific language impairments in children (pp.
17–34).
Baltimore
: Paul H. Brookes.
-
Tomblin, J. B.,
Freese, P. R. &
Records, N. L. (1992). Diagnosing specific language impairment in adults for the purpose of pedigree analysis.
Journal of Speech and Hearing Research, 35, 832–843.
-
van der Lely, H. K. J. &
Howard, D. (1993). Children with specific language impairment: linguistic impairment or short-term memory deficit
Journal of Speech and Hearing Research, 36, 1193–1207.
-
Walley, A. C. (1993). The role of vocabulary development in children's spoken word repetition and segmentation ability.
Developmental Review, 13, 286–350.
-
Wechsler, D. (1974). Wecksler Intelligence Scale for Children Revised (Anglicised version).
New York
: Psychological Corporation.